

Author: Leisha Living Ground
On January 6th, the dream and vision of Living Ground ~ Suelo Vivo was presented to the community here in Southern Ecuador. The intention was to share hope that, together, we could actually enact a solution to the state of affairs we are all facing and enduring. I do feel many of us know what the problem is. Here is a solid “soilution”!
Are we ready?!
A US Foundation (whose intention is global food sovereignty) gifted us with a tractor and a Mighty Mike Microbe Compost turner. A huge gift that enables us to make massive amounts of biologically rich compost. The Foundation’s name is “River of Kindness” So, we have the equipment. Over the past two years, I have been in actively studying and applying experiential knowledge of the teachings of Dr Elaine Ingham (www.soilfoodweb.com). We have the knowledge. We have negotiated a long term lease on land and a potential to purchase two parcels. We have the land. Now, we need the team and the financial means to make this happen. Call me crazy, but I see it all coming together easily.
As I shared in the presentation on January 6th (see video below), I have no intention of “running” a business nor do I wish too. BUT THIS IS IMPORTANT. I would much prefer to walk next to others in this dream as a group. So, I am giving it my best shot to inspire others to collaborate. If it doesn’t work, I just make a lot of compost and share with clients who want to regenerate in a small scale. We are gearing up to do a fundraiser and that will be announced soon.
THE PODS & LEADERS
We need leaders to rise with intention and focus. At the workshop, many did sign up for PODs. This is an amazing opportunity at so many levels. Not only can we regenerate the soils and remove the harmful chemicals and sprays seeping into our food system, we can harvest amazing results at all levels of existance from the smallest of the microbes to the human being. We can reduce farmers/growers input costs; we can reduce water needs; we can increase crop yields; and, my favourite, we can ensure plants have nutritional fullness (human health). This Operation Microbes means everyone wins (profits). It really is a win/win/win!
The vision….
It will be an education center, hang out, and fully alive business. Everyone will win. Profit sharing is horizontal so everyone benefits.
Can you see it?
Here is a view of the presentation in English and Spanish (and, sorry, it announces this is January 22nd…I really do not know what the date is anymore…it was January 6th).
For the creation of Living Ground, Suelo Vivo, to happen, we need to rise and educate POD leaders. That was the intention of the presentation. There are nine PODS each having equal worth to the bigger whole. All PODS are formed on the foundation of the “good guy” microbes. Whether it be the compost makers, testers (lab techs), growers, artists, gourmet market operators, distillery creators (essential oils) they all connect to the infusion and presence of the microbes. We are mearly the creative force in the “soil food web” rising its’ importance (foundational) so all thrive and benefit.
For more details on the POD descriptions (listed below), view the POD CREATION SHEET
I also encourage everyone and all interested parties to connect on the Living Ground Telegram Channel
The Operations Microbe goal is rise up and inspire 2 POD leaders for each section (preferably one local and one gringo) who will be fully trained and mentored in the creation process. The leaders will be linked together to ensure all teams are working with integrity, empowerment and inspiration. Each leader will be trained in Tools and Art of Sacred Commerce. All training will be offered freely in exchange of the commitment to make this happen.
It is my commitment to offer all training (whether in the operations and understanding of the microbes, soil food web or sacred commerce) to all those who show up. If the team member chooses not to continue with the creation, there will be an agreement made that training costs will be reimbursed. There really does need to be a common vision and a selfless commitment towards this creation. My effort will be given and shared only for those who really do want to put this dream into action.
For those who attended the workshop on January 6th and signed up for the PODS, you have been added to the mailing and communication lists. If you are interested in a POD after watching the presentation video, please contact me EMAIL
mailto:info@livingground.art
We are now preparing to raise the necessary funds for “Operation Microbe” set-up. Here are the PODS…
Full Financial Requirements for “Operation Microbe Creators”
BREAK DOWN OF THE PODS
Compost Makers ~ Microbe Makers | Build Microbe Compost, Teas & Extracts. Two Team Leaders (Gringo/Local) |
Lab Techs ~ Microbe Testers | Laboratory Soil Testing of the Microbes Two Team Leaders (Gringo/Local) |
Consultancy Team Microbe Infusers |
Off Site Consultancy to regenerate lands, farms and gardens. . Two Team Leaders (Gring/Local) and a team of compost workers. Must be fully trained in understanding the soil tests, compost and applications to regenerate land (including removal of toxins, chemicals and toxins) |
Distiller | One Team Leader with team Creation of pure essential oils and operations of the stills. Bottlings and labeling |
Onsite Gardener and Grower Microbe Planters |
On site part time Potting of plants and seeds for sale |
TiendaOperation ~ Microbe Sales | Two Team Members (Gringo and Local) Operations of the Microbe Market that will showcase Microbe products and produce. Tea/Tapa Bar and making of food and offerings. |
Off Site Microbe Artists | Microbe Creatives Product makers but the base must be all products are connected to the microbes |
Off Site Microbe Growers | Produce to sell in the Tienda/Market or used for Essential Oil making |
As above, so below! Up, up and away!
Listen to the Music of the Tardigrade (the little bear of the soil)
…The Soil Biology Primer represents a new era in our agency’s soil science contributions to natural resource conservation. In the past we have focused primarily on the chemical and physical properties of soil . This publication highlights another integral component of soil , its biological features. The Primer explains the importance of biological functions for productive and healthy agricultural systems , range lands, and forest lands.
The Soil Biology Primer is intended for farmers, ranchers, agricultural profes sionals, resource specialists , students, teachers, and NRCS conservationists, specialists , and soil scientists as a reference for enhanced understanding of the critical functions performed by soil life. I hope you enjoy reading about the fascinating diversity of soil life under our feet and gain a deeper appreciation of the intrinsic value of soil organisms to sustainable civilizations . Protecting our Nation’s soil for future generations is of greatest importance.
ENJOY click to read, explore, learn, download……
Soil. It’s our greatest treasure.
It can take hundreds of years and many natural processes to make even a centimetre of soil. The mechanical and chemical weathering of rock makes up around half of any soil’s composition, with around 5% supplied by organic material, and the rest made up by air and water.
Put another way, soil is a complicated mix of both the non-organic, abiotic components- minerals, water and air, and the organic biotic components- bacteria, archaea, fungi, plants and invertebrates that live and die within it.
In addition, and bound together with any basic discussion about soil, is the reality of a living soil, the soil food web and soil biodiversity. Soil is a complex, sustainable and dynamic ecosystem, sustained through the complicated interaction of countless soil fauna like worms, woodlice, springtails, nematodes and mites, together with fungi and bacteria.
“Despite all our achievements, we owe our existence to a six-inch layer of topsoil and the fact that it rains.”
However, within a few generations, we have seen the world’s soils rapidly and increasingly degrade, losing nutrients, carbon and fertility, turning saline or actually blowing away. Crops are losing yield and not responding to NPK fertilisers. Fields and farms are being abandoned across much of the world, forcing even more poverty, suffering and human migration. This degrading is mostly human-driven, due to bad farming practices, pollution, acidification, compaction, deforestation and climate change across the world. It’s a sobering and worrying time. Soil biodiversity is dying, with soil fauna like springtails and soil mites reducing to almost zero. Worms are disappearing, fungal activity ceasing.
Soil scientists and farmers are finally being listened to. People are learning and gaining more knowledge and understanding. Research is now well funded and positive changes are being discussed at a governmental level and implemented on a regional and local level. Sustaining, improving and increasing soils is a lengthy and time consuming process, but no dig, microbe compost making and regenerative agriculture are showing great results. Feeding the soil rather than the plant has become a well known mantra amongst gardeners and organic growers. The ship may be sinking, but all is not lost.
Whoever you are and whoever you will become, tread lightly on the earth.”
In am world that has gone mad with sexual orientation, let me introduce Meosis!
And Haploids..who love working together.
When they reach fusion, dipoilds happens. The process is Plasmogamy!
There is an internet of nature that we are just beginning to understand. It is absolutely amazing and we are just beginning to understand and be able to measure. Together the soil food web and the trees work harmoniously. Here is a video which explains it very well, simply!
Super cool webinar!
Compassion of the work we are doing..and should be doing!
Is your favourite fruit about to go extinct?
The deadly disease pathogen Fusarium wilt TR4 (previously referred to as Panama Disease) has been wreaking havoc and ravaging the $25 billion global banana industry – with infected plantations experiencing 100% loss and being quarantined for decades. Colombia has already declared a National State of Emergency, but it may be too late. A flurry of apocalyptic media accounts have followed, revealing a race to save bananas from extinction after the disease has left a trail of scorched banana plantations in its wake.
The world’s most destructive banana disease is spreading, and there are currently no chemicals available to kill the disease. This might be a blessing in disguise as it is highly likely that chemical use has actualy contributed to this problem in the first place.
In August 2021, the Ecuadorian Government has raised the banana disease Fusarium wilt TR4 to pandemic level. “Ecuador’s message to the global banana community is clear: Fusarium is not just a pest; it is a lethal pandemic for bananas that currently has no solution and that threatens one of the most important industries for the Ecuadorian economy.”
Fusarium wilt is a common fungal disease that attacks many types of herbaceous plants, including banana trees. Also known as Panama disease, fusarium wilt of banana is difficult to control and severe infections are often deadly. The disease has decimated crops and has threatened an estimated 80 percent of the world’s banana crop. Read on to learn more about banana fusarium wilt disease, including management and control. Banana Fusarium Wilt Symptoms Fusarium is a soil-borne fungus that enters the banana plant through the roots. As the disease progresses upward through the plant, it clogs the vessels and blocks the flow of water and nutrients. The first visible banana fusarium wilt symptoms are stunted growth, leaf distortion, and yellowing, and wilt along the edges of mature, lower leaves. The leaves gradually collapse and droop from the plant, eventually drying up completely. A good article https://draxe.com/health/banana-fungus/
The good news is there probably is a natural organic solution, simply utilizing the natural defense mechanism of microbes.
https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2672.2006.03083.x
https://www.frontiersin.org/articles/10.3389/fmicb.2019.00616/full
Fusarium Wilt is a problem in the soil…a bad guy is taking over! Raise the good guys and let them do their magic!
Bananas As We Know Them Are Doomed VICE News
Disease Is Ravaging the $25 Billion Banana Industry Bloomberg
Why The World’s Most Popular Banana May Go Extinct Business Insider
The world’s bananas are in trouble BBC World Service
Why The Banana Business Of Chiquita And Dole Is At Risk CNBC
Not All Viruses Are Bad For You. Here Are Some That Can Have a Protective Effect
CYNTHIA MATHEW, THE CONVERSATION10 AUGUST 2019
Viruses are mostly known for their aggressive and infectious nature.
It’s true, most viruses have a pathogenic relationship with their hosts – meaning they cause diseases ranging from a mild cold to serious conditions like severe acute respiratory syndrome (SARS). They work by invading the host cell, taking over its cellular machinery and releasing new viral particles that go on to infect more cells and cause illness.
But they’re not all bad. Some viruses can actually kill bacteria, while others can fight against more dangerous viruses. So like protective bacteria (probiotics), we have several protective viruses in our body.
Protective ‘phages’
Bacteriophages (or “phages”) are viruses that infect and destroy specific bacteria. They’re found in the mucus membrane lining in the digestive, respiratory and reproductive tracts.
Mucus is a thick, jelly-like material that provides a physical barrier against invading bacteria and protects the underlying cells from being infected. Recent research suggests the phages present in the mucus are part of our natural immune system, protecting the human body from invading bacteria.
Phages have actually been used to treat dysentery, sepsis caused by Staphylococcus aureus, salmonella infections and skin infections for nearly a century. Early sources of phages for therapy included local water bodies, dirt, air, sewage and even body fluids from infected patients. The viruses were isolated from these sources, purified, and then used for treatment.
Phages have attracted renewed interest as we continue to see the rise of drug resistant infections. Recently, a teenager in the United Kingdom was reportedly close to death when phages were successfully used to treat a serious infection that had been resistant to antibiotics.
Nowadays, phages are genetically engineered. Individual strains of phages are tested against target bacteria, and the most effective strains are purified into a potent concentration.
These are stored as either bacteriophage stocks (cocktails), which contain one or more strains of phages and can target a broad range of bacteria, or as Adapted bacteriophages, which target specific bacteria.
Before treatment, a swab is collected from the infected area of the patient, cultured in the lab to identify the bacterial strain, and tested against the therapeutic phage stocks.
Treatment can be safely administered orally, applied directly onto wounds or bacterial lesions, or even spread onto infected surfaces. Clinical trials for intravenous administration of phages are ongoing.
Beneficial viral infections
Viral infections at a young age are important to ensure the proper development of our immune systems. In addition, the immune system is continuously stimulated by systemic viruses at low levels sufficient to develop resistance to other infections.
Some viruses we come across protect humans against infection by other pathogenic viruses.
For example, latent (non-symptomatic) herpes viruses can help human natural killer cells (a specific type of white blood cell) identify cancer cells and cells infected by other pathogenic viruses. They arm the natural killer cells with antigens (a foreign substance that can cause an immune response in the body) that will enable them to identify tumour cells.
This is both a survival tactic by the viruses to last longer within their host, and to get rid of competitive viruses to prevent them from damaging the host. In the future, modified versions of viruses like these could potentially be used to target cancer cells.
Pegivirus C or GBV-C is a virus that does not cause clinical symptoms. Multiple studies have shown HIV patients infected with GBV-C live longer in comparison to patients without it.
The virus slows disease progression by blocking the host receptors required for viral entry into the cell, and promotes the release of virus-detecting interferons and cytokines (proteins produced by white blood cells that activate inflammation and removal of infected cells or pathogens).
In another example, noroviruses were shown to protect the gut of mice when they were given antibiotics. The protective gut bacteria that were killed by the antibiotics made the mice susceptible to gut infections. But in the absence of good bacteria, these noroviruses were able to protect their hosts.
The future of therapeutic viruses
Modern technology has enabled us to understand more about the complexities of the microbial communities that are part of the human body. In addition to good bacteria, we now know there are beneficial viruses present in the gut, skin and even blood.
Our understanding of this viral component is largely in its infancy. But it has huge potential in helping us understand viral infections, and importantly, how to fight the bad ones. It could also shed light on the evolution of the human genome, genetic diseases, and the development of gene therapies.The Conversation
Cynthia Mathew, Research Assistant, University of Canberra.
This article is republished from The Conversation under a Creative Commons license.
Land degradation is a collective threat for everyone. It is vitally important we make a transition to regenerate our soils which as a primary basis of all life and health. THis is a paradigm shift in our way of thinking and doing. Our mission is to both educate and create bio-complete soils and spread this gold for our collective future. It is about changing our approach (even the organic approach) and entering a new paradigm shift. It is about empowering everyone to thrive, win and benefit. It is about creating compost that rejuvenates soils, educating everyone into this knowledge and creating a system where everyone wins.
* Establish Microbe Compost Creation and Microscope Laboratory
* Consult, Educate and Empower both locals and all food growers.
* Transform neighborhoods here and in Ecuador
* Protect sacred lands and WATER-SHEDS and offering them a solution towards the transformation
* Grow food that is truly nutrient rich and which becomes our medicine.
* Create a reproducible model of sustainability to share our knowledge.
The concept: Beneficial organisms convert and create life, nutrients, energy, health and bountiful ecosystems. Our mission is create rich compost, to teach and educate, assist, convert and inspire conversion to regenerative cultivation This creates abundance for everyone. . Let’s heal the living world together.
We have a natural way forward for Sustainable Agriculture and Human Health blending science and art.
REGENERATIVE ORGANIC stewardship
It’s Time! It’s Necessary!
flyerlivingground support
We are a little team whose backgrounds and heritage merges from all over the world (England, Canada, USA, Ecuador). We come together in this project to make a difference, help our community and expand out into the farms of lands of Ecuador. Our backgrounds are diverse but we all love the land and nature. Our common dream is to change the world for our sakes and the sake the generations to come
The most common conception of corruption is the theft of public money through unscrupulous methods. However, there are many other ways to deceive the public and one of the most notorious is the promotion of industrial chemical agriculture.
Most people in Ecuador, visitors and residents believe that the food is natural and therefore organic. Nothing could be further from the truth. Only 0.3% of the 14 million agricultural hectares are certified organic. That means that those farms have to conform to a rigid process of certification. In the U.S., by the way, the Federal Department of Agriculture allows farmers to use pesticides and still be considered organic.
There are rural campesinos that do not use excessive nitrogen and pesticides, but they are very few and many of them do not follow acceptable practices of not using fresh manure to fertilize plants.
The reality is that almost all farmers, with a few exceptions, are controlled by an industry that has zero interest in the quality or nutritional quantity of the food.
The Big 6 becomes the Big 3
Last year there were the Big 6 and today there are only the Big 3. Bayer bought Monsanto, DOW and DuPont merged and ChemChina bought Syngenta. They combine for about $375 billion in sales in a $450 billion market worldwide of chemical and biological amendments in agriculture.
The concentration of capital is due to over-production and increased competition at a time when farmers are beginning to reject chemicals. India is the best example with the hundreds of suicides due to destroyed families from high costs of the chemicals and lost production. The chemical industry is now switching to biologic products. That may appear to be good but it is not because it follows the same philosophy, but with a different product. I will explain in a minute.
Small farmers are hurt by ag-industry practices too.
The results from the intensive approach from the chemical ag-industry in Ecuador are devastating. They now control the entire university system, so that any agricultural engineer in the country gets almost no training in soil microbiology. There is absolutely no focus on true food nutrition and what used to be a sovereign food system — that is now as foreign as the salchipapas are to the traditional diet.
The excessive use of urea that is freely distributed by the government through the Ministerio de Agricultura Y Ganadería (MAGAP) is the prime reason for toxic watershed system which causes cancer in humans and animals alike and can only be filtered out with active carbons filtering.
The soils are loaded with salts from the excessive use of chemicals and fertilizers which requires the excessive use of irrigation and increasing erosion everywhere. Ecuador has lost between 20 and 40% of the organic material that normally occupies the top 10 inches of soil. The constant tillage to increase production has freed millions of tons of carbon normally sequestered in the soil upon which the bacteria and fungus use for 50% of their diet, not to mention the destruction of the mycorrhiza and bacterial species that have existed or millions of years.
The UN report on Trade and Commerce published in 2013, “Wake Up Before It Is Too Late” pointed out that the largest contributor to global warming and the green-house effect is industrial agriculture which accounts for 71% of all carbon in the atmosphere. In Ecuador, that means increased flooding on the coast and loss of glaciers and the eventual evaporation of the original 235 glacial lakes in the Cajas Mountains, west of Cuenca.
The impact on health
The worst impact is on health. There are over 450 chemicals that make up the more than 9,000 pesticide compounds that have been directly attributed to non-infectious disease and are now in epidemic form. These include 35 cancers of which 3% of occur in children, as well as other childhood diseases including autism, type 1 diabetes. In the general population, allergies, asthma, depression, Parkinson, Alzheimer’s, metabolic syndrome problems, depression, sexual reproduction, etc., are also on the increase.
The average life span in Ecuador is going down, the use of pharmaceutical drugs is going up and farmers under pressure to increase production are using more chemicals.
The proposal from the former president Correa and current vice president Glas to use transgenic (GMO) seeds is nothing more than a continued policy of chemical additives with a punch that will permanently make glyphosate as natural as DDT until the world rejected it.
The only reason to use GMO is to make money for the multinational companies. The effects of the GMO are absolutely astounding and incredibly horrendous to the entire population. The introduction of any seeds will destroy whatever native population that existed before in short order as a result of cross pollination. The seed producers own patents and have the right to take over any production if the seed was not purchased from the manufacturer. Over 80% of all GMO is packaged with glyphosate which means that pregnant women who consume food produced with that GMO seeds will have glyphosate in their blood during and lactating milk which will then be fed to their children.
The combined effect of the intensive chemicals in the agricultural industry and GMO products has literally destroyed any semblance of a healthy population and the source of food for the future, the soil.
Is this not a corrupt industry?
Ag industry bio products
Let me go back to an earlier point: biological products. Let’s start with a simple lesson in plant development.
Plant development depends on photosynthesis, which uses solar energy to combine with carbon from the air to produce simple proteins, carbohydrates and simple sugars within the plant system. About half of these nutrients are used by the plant for growth and metabolic processes but the rest goes to the roots.
In trees, about 85% of nutrients support the roots while in grasses it is about 35%. Why? The plant releases almost 100,000 phytochemicals called exudates to attract microorganisms, bacteria and fungus. The microorganisms live within 1 to 2 cm. of the roots and are attracted to eat the phyto chemicals. The bacteria and fungus secrete an enzyme that breaks down the crystalline structure of soil aggregates of sand, silt and clay to release minerals in soluble form that eventually gets consumed by the plants.
The plant knows what it needs based on which stage of plant development it is in, such as stalk, branch, leaf, flower and fruit development. How many microorganisms does the plant require? More than a hundred thousand different species in the quantity of many millions of each.
The agricultural industry sells about 5 to10 different microorganisms because it is easy to replicate them. The plant needs hundreds of thousands. What is the problem? The large variety of microorganisms facilitate plant stimulation and the immune system against pests. The limited approach of a few falls short.
In addition and more importantly, humans need between 80-90 trace minerals a day and the only way to get them is if the food comes with a rich variety of minerals and that can only happen with an agriculture that is based on rich microbiology. There is no other way. When people refer to their products being agroecological, they interpret natural use of fertilizer as being organic. It is not. True agroecological production is totally based on the scientific application of microorganisms produced from the very same soil location, not from the US to be used in Ecuador. This is why Denver and Canada could not produce quinoa successfully; same altitude and climate but different soil and microorganisms.
Food produced by microbiological methods will have between 40% and 500% more minerals, antioxidants, vitamins and probiotic bacteria. This is why there is a health crisis. There are a lot of people in Tungurahua, Chimborazo and Bolivar provinces who have thyroid problems. The food they used to eat more than a generation ago that was semi organic had 5 times more iodine than the current food and if they do not buy iodized salt, they are going to have metabolic problems with the thyroid. This is one example of many.
The best example of the benefits of eating organic food is Okinawa, Japan where people live far longer lives than the average by consuming a high organic vegetable diet with a little fish and no meat products. That is another story but the key is the consumption of organic vegetables.
On my farm, we produce a very rich microbiome in the compost that we then use to extract the microbiology and spray the gardens and fruit trees. No pests, no worries with higher production yields. I am working with farmers around the country to advance these techniques through teaching and advocacy.
_________________
Shelly Caref retired to Ecuador after working as an engineer and mid level manager in the high tech industry for multinational companies. He and his wife, Nelly, discovered that using chemicals in agriculture had direct linkages that caused her illnesses, his daughters breast cancer and his granddaughters type 1 diabetes. He began a five year journey of discovery, investigation and experimentation to fully understand what is “biological agriculture” and why it is the only way to produce food. He can be reached at scaref@gmail.com The ebook can be purchased in English at https://www.smashwords.com/books/view/648740
Biology of the sunshine vitamin
“Vitamin D is unique because it can be made in the skin from exposure to sunlight.[3,8–10] Vitamin D exists in two forms. Vitamin D2 is obtained from the UV irradiation of the yeast sterol ergosterol and is found naturally in sun-exposed mushrooms. UVB light from the sun strikes the skin, and humans synthesize vitamin D3, so it is the most “natural” form. Human beings do not make vitamin D2, and most oil-rich fish such as salmon, mackerel, and herring contain vitamin D3. Vitamin D (D represents D2, or D3, or both) that is ingested is incorporated into chylomicrons, which are absorbed into the lymphatic system and enter the venous blood. Vitamin D that comes from the skin or diet is biologically inert and requires its first hydroxylation in the liver by the vitamin D-25-hydroxylase (25-OHase) to 25(OH)D.[3,11] However, 25(OH)D requires a further hydroxylation in the kidneys by the 25(OH)D-1-OHase (CYP27B1) to form the biologically active form of vitamin D 1,25(OH)2D.[3,11] 1,25(OH)2D stimulates intestinal calcium absorption.[12] Without vitamin D, only 10–15% of dietary calcium and about 60% of phosphorus are absorbed. Vitamin D sufficiency enhances calcium and phosphorus absorption by 30–40% and 80%, respectively.[3,13]”
https://ods.od.nih.gov/factsheets/vitamind-healthprofessional/
This article was written by Tim Spector from King’s College London and was originally published by The Conversation.
Everyone loves D, the sunshine vitamin. Doctors, patients and the media have been enamoured with vitamin D supplements for decades. As well as their clear benefit in curing severe vitamin D deficiencies, endless headlines hail their magical ability to reduce a vast range of conditions from dementia to cancer.
Medical specialists such as myself have been promoting supplements to our patients with osteoporosis and other bone problems for decades. Many food products contain artificially added vitamin D with the aim of preventing fractures and falls and improving muscle strength although the vitamin also has been claimed to boost the immune system and reduce ageing. I used to sometimes take vitamin D myself and recommended it to my family to survive sun-starved winters.
However, a new paper on the risks that vitamin D may pose finally has convinced me that I was wrong. My view on vitamin supplements and the multi-billion dollar industry behind them altered radically after I began researching my book, The Diet Myth, in 2013. The industry and its PR is supported by celebrities who reportedly have high-dose vitamins drip fed into their veins, and around 50 percent of Americans and Britons take them regularly. But surprisingly, there is a lack of evidence to support the health benefit claims of virtually all vitamin supplements on the market.
One study based on the large SELECT trial suggested that supplements such as vitamin E and selenium actually increased prostate cancer in some men. And last year massive analyses combining 27 studies on half a million people concluded that taking vitamin and mineral supplements regularly failed to prevent cancer or heart disease. Not only are they a waste of money for the majority of us – but if taken in excessive quantities they can actually hasten an early death, increasing your risk of heart disease and cancer.
Virtually no vitamins or supplements have actually been shown to have any benefit in proper randomised trials in normal people without severe deficiencies. Rare exceptions have been lutein nutrients for macular degeneration, a common cause of blindness – and vitamin D, the golden boy of vitamins.
Since the 1980s, researchers (including myself) have written thousands of papers, associating a lack of our favourite vitamin with over 137 diseases. A 2014 BMJ report, however, found these links mainly to be spurious.
Won’t do you any harm?
Our genetic makeup influences vitamin D levels. We can use this information to tell if naturally low vitamin D levels might actually increase the risk of disease (rather than be a consequence of it). The evidence so far suggests (with the possible exception of multiple sclerosis and some cancers) that low vitamin D levels are either irrelevant or merely a marker of the disease.
Until now we haven’t worried about giving people extra vitamin D because we thought “it might help anyway and of course (as it’s a vitamin) doesn’t do you any harm”. With our increasing knowledge, we should now know better. Recent studies in the last five years have suggested that even calcium supplements as well as being ineffective in preventing fracture can increase the risk of heart disease.
While several studies in normal people failed to find any protective effects from vitamin D, others have been more worrying. One 2015 randomised study of 409 elderly people in Finland suggested that vitamin D failed to offer any benefits compared to placebo or exercise – and that fracture rates were, in fact, slightly higher.
The usual prescribed dose in most countries is 800 to 1,000 units per day (so 24,000-30,000 units per month). However, two randomised trials found that at around 40,000 to 60,000 units per month Vitamin D effectively became a dangerous substance.
One study involving over 2,000 elderly Australians, which was largely ignored at the time, and the one just published found that patients given high doses of vitamin D or those on lower doses that increased vitamin D blood levels within the optimal range (as defined by bone specialists) had a 20-30% increased rate of fractures and falls compared to those on low doses or who failed to reach “optimal blood levels”.
Explaining exactly why vitamin D supplements are often harmful is harder. Some people who don’t take supplements have naturally high blood levels which may be due to them spending large amounts of time outdoors in the sun or eating oily fish regularly – and there is no evidence that this is harmful. Higher than average levels can also be due to genes which on average influence about 50 percent of the differences between people. So our obsession with trying to bring everyone up to a standard normal target blood level is seriously flawed, in a similar way to our one-size-fits-all approach to diet.
Until now we have believed that taking vitamin supplements is “natural” and my patients would often take these while refusing conventional “non-natural” drugs. Our body may not view supplements in the same misguided way. Vitamin D mainly comes from UV sunlight converted slowly in our skin to increase blood levels or is slowly metabolised from our food.
In contrast, taking a large amount of the chemical by mouth or as an injection could cause a very different and unpredictable metabolic reaction. For example, our gut microbes are responsible for producing around a quarter of our vitamins and a third of our blood metabolites and also respond to changes in vitamin levels picked up by receptors in our gut lining. Any artificial addition of large amounts of chemicals will upset some sensitive immune processes.
The news that even my favourite vitamin can be dangerous is a wake-up call. We should be taking our worldwide abuse of these chemicals much more seriously rather than routinely adding them to foods. The billions we waste on these products, assisted by the poorly regulated but rich and powerful vitamin industry should be spent on proper healthcare – and people should be educated to go in the sunshine and eat a diverse range of real food instead. For 99 percent of people, this will provide all the healthy vitamins they will ever need.
Tim Spector is a professor of Genetic Epidemiology at King’s College London.
This article was originally published by The Conversation. Read the original article.
A human body consists of about ten times more bacterial cells than human cells, the majority of which are in the gut. The ratio of microbial to human genes is even more impressive, counting more than 3 million microbial genes compared with 22,000 human genes. The gut microbiome starts to develop before birth and becomes fully established 2–3 years into childhood. The formation of the infant microbiome is not only important for gut function, but also crucial for the development of the systemic and mucosal immune system thereby influencing infant and eventually adult health (Lozupone et al, 2012).
… since microbes from fruits, salads and vegetables join the human gut microbiome, the plant microbiome can affect the gut microbiome and thereby human health.
The original view of a simple mutualistic interaction between gut cells and microbial cells has given way to a much more complex and dynamic view of a close symbiotic interaction between humans and bacteria. The intestinal epithelial and mucosal immune cells recognize and interact with select bacterial species which contribute to the proper functioning of the human immune system. Microbially generated metabolites not only help the gut to extract nutrients from food, but can also influence immune function (Postler & Ghosh, 2017). In fact, a dysfunctional gut microbiome has been shown to cause or contribute to various gastrointestinal diseases, inflammatory or immune‐mediated diseases, diabetes, obesity, atopic diseases and chronic kidney diseases (Lozupone et al, 2012). Generally, microbiome richness and diversity are directly associated with human health, but this simple equation needs to be considered with care.
An important step towards our current understanding was the finding that healthy and sick gut microbiomes differ in their microbial composition. Although gut microbiomes contain up to 1,000 different microbial species and show large variations between individuals, 99% of the gut microbiota belongs to only 30–40 species (Lozupone et al, 2012) that change in positive or negative ways in response to external or environmental factors. Novel sequencing techniques now allow the detection and quantification of virtually all gut microbes, but we still know almost nothing about the role and function of many microbial species, let alone the role of viruses that also populate the gut ecosystem.
As humans and human civilization changed over millennia so did the human gut microbiota in response to changes in diet. The gut microbiome of contemporary hunter–gatherer societies for instance shows drastic changes during the year reflecting the changes in food supply. Moreover, major differences can also be observed between the microbiota of female and male members of these societies: the microbiota of women resembles more those of herbivores, while the male members have a more carnivore‐like microbiome. The changes in gut microbiota from earlier to modern civilizations also reflect changes in hygiene, which can still be observed between urban and rural communities. Modern lifestyle with improved hygiene, processed food and the widespread use of medicines, notably antibiotics, seems to have had a major effect on human gut microbiome diversity during the past decades, overall reducing its variety.
Importantly, what people eat has a much stronger influence on the gut microbial composition than genetics: members of the same family living in different locations show larger differences in their microbiomes than genetically unrelated individuals who share the same household and similar lifestyle and nutrition.
Humans can only synthesize 11 of the 20 essential amino acids themselves; they rely on food intake for the other nine along with all 13 essential vitamins. Most of these amino acids and vitamins are retrieved from meat, eggs, milk products, fruits and vegetables, but a few essential compounds are produced by microbes—which are important producers of essential amino acids and vitamins themselves. For example, cobalamin (Vitamin B12) cannot be produced by either plants or animals; it is synthesized by microbes in the plant microbiotas or in the gut of ruminant animals.
In addition to primary metabolites, amino acids and vitamins, many microbes also produce a large variety of chemicals known as secondary metabolites or natural products. Among the best‐known of these compounds are antibiotics but also immunosuppressants, anticancer and anti‐inflammatory drugs.
Yet, plants are at least as capable as microbes in producing secondary metabolites; overall plants synthesize more than hundred thousand compounds, many of which are used as pharmaceuticals or are important for human health. Flavonoids, a highly diverse class of plant compounds that are present in many fruits, vegetables or nuts, have many biological activities including anti‐inflammatory, anticancer and anti‐viral properties. Omega‐3 (n‐3) polyunsaturated fatty acids (PUFA) are found in nuts and seeds of twenty different plants, including soy bean, rape seed or flax. PUFA reduce the risk of cardiovascular diseases, blood pressure and inflammatory reactions. Another class of important plant products are conjugated linoleic acid, L‐carnitine, choline or sphingomyelin, which all positively affect the gut microbiome (Postler & Ghosh, 2017). Interestingly, many plants produce only tiny amounts of these secondary metabolites, but beneficial microbes associated with their plant host can boost their production. The interaction of microbes and plants thereby influences food quality, taste and texture (Flandroy et al, 2018).
Food production has changed tremendously during the past century. Today’s agricultural production systems are mostly large‐scale monocultures of a few elite crop varieties that require fertilizers, herbicides and pesticides to ensure a high yield. Most of these high‐yield breeds have lost important secondary metabolites that protect plants and humans alike. A good example is the domestication of plants of the Brassicacae family, such as cabbage and cauliflower, in which the amount of glucosinolates has been reduced to eliminate their bitter taste. Yet, glucosinolates not only help the plant to resist to pathogens but are also suspected to be a prebiotic anticancer metabolite (Blum et al, 2019).
Modern lifestyle with improved hygiene, processed food and the widespread use of medicines, […] seems to have had a major effect on human gut microbiome diversity during the past decades
Industrial agriculture requires increasing amounts of fertilizers and pesticides to maintain yield. This seems to be the result and/or the cause of a poor microbial diversity in the soil. Soil erosion and climate change also affect microbial biodiversity and contribute to the loss of large areas of arable land and their microbial populations (Blum et al, 2019). In this way, crop plants today lack many of their important symbiotic partners to produce or increase the contents of vitamins, minerals, antioxidants and other metabolites that are beneficial for both plant and human health.
Soil is the ultimate source from which plants recruit beneficial microbes for the rhizosphere and phyllosphere, that is the root and shoot surfaces, but also for the inner plant organs (endosphere), including fruits and seeds. Plant rhizo‐, phyllo‐ and endosphere microbes not only increase nutrient use efficiency and thereby crop yield, they are also involved in enhancing resistance against herbivores, insects, bacterial and fungal pathogens and even nematodes or viral infections (Blum et al, 2019).
The use of herbicides, excessive mineral fertilization and improper land management have serious effects on microbial communities. A good example is glyphosate that has been used for more than 40 years in agriculture. This chemical inhibits enoylpyruvylshikimate‐5‐phosphate (EPSP) synthase, an enzyme of the shikimate pathway that is responsible for the biosynthesis of aromatic amino acids in plants. EPSP synthase is present in all plants but not in humans, which makes glyphosate an ideal herbicide. The application of glyphosate to kill weeds is linked with the use of glyphosate‐resistant crops which has helped considerably to assure high crop yields.
But the use of glyphosate might come with a price. Although the acute toxicity of glyphosate to humans is low, the fact that humans are exposed to it over long terms prompted the WHO to classify glyphosate as a potential carcinogenic in 2015. Importantly, glyphosate is also an antimicrobial, as both bacteria and fungi rely on the shikimate pathway for aromatic amino acid production. A number of reports show negative effects on beneficial soil, rhizosphere and endosphere microbes, including arbuscular mycorrhizal fungi and nitrogen‐fixing Rhizobium spp. (Van Bruggen et al, 2018). Glyphosate also seems to inhibit a number of soil, plant and gut beneficial microbes at much lower concentrations than pathogenic microbes. In terms of the human gut microbiome, such inhibition was observed for the beneficial microbes Bifidobacterium sp. and Enterococcus sp. compared with pathogenic strains of Clostridium sp. and Salmonella sp. (Van Bruggen et al, 2018). Overall these indirect effects of glyphosate on soil, plant and human microbes might affect human health.
The protein‐rich input from increased meat consumption in Western diets also massively affects the gut microbiome, whereby certain microbes suppress beneficial competitors and change our eating behaviour to favour more unhealthy food. Much of the current discussion on maintaining a diverse and healthy gut microbiome is focused on eating a healthy diet, which is defined by a high content of fibre, minerals and vitamins. However, this still leaves out an important aspect of food.
Most of our daily food comes from industrial agriculture and has been exposed to herbicides, fertilizers and a large array of pesticides to obtain high yields. Pesticides are a large class of chemical compounds that include fungicides, bactericides, nematicides, molluscicides, avicides, rodenticides and animal repellents. A large literature is available to show the negative effects of many commonly used pesticides on human health. For example, various carbamates, pyrethroids and neonicotinides have endocrine‐disrupting activity and negative effects on reproduction in animals and humans (Nicolopoulou‐Stamati et al, 2016). However, many beneficial microbes are also among the targets of pesticides with direct and indirect implications on soil, plant and food safety.
The interaction of microbes and plants thereby influences food quality, taste and texture.
For example, most copper‐based fungicides have a deleterious effect on nitrogen‐fixing bacteria (Meena et al, 2020). Similarly, long‐term application of organomercurials has negative effects on cellulolytic fungal species. Triarimol and captan decrease the content of Aspergillus fungi that help plants to grow and develop. Carbendazim is highly toxic to Trichoderma harzianum, a potent biocontrol agent against the soil‐borne fungal pathogens Fusarium, Pythium and Rhizoctonia and many fungicides also inhibit hyphal growth and root colonization by arbuscular mycorrhizal fungi. The insecticides chlorpyrifos, phosphamidon, malathion, fenthion, methyl phosphorothioate, parathion, chlorfluazuron, cypermethrin or phoximin have negative effects on soil and rhizosphere microbiota at field‐recommended concentrations (Meena et al, 2020).
Many fresh fruit, salads and vegetables are stored and shipped, often over long distances, before they arrive at the supermarket. Long storage and shipping periods, however, are not possible without treating fruit and vegetables with a variety of pesticides and antibiotics for preservation. Not only will some of these chemicals make their way through food into the human gut, but they also kill off the plant microbiota.
Agriculture uses about four times more antibiotics than human medicine. This massive (ab)use of antibiotics in farming, mostly to enhance growth and health of livestock, has greatly contributed to the emergence of resistant bacteria. Not only do antibiotics excreted by animals change microbial function and composition of soil, waterways and other biotopes but also the antibiotic resistance genes can spread to other microbes via horizontal gene transfer (Jechalke et al, 2014). The consumption of fresh produce from fields fertilized with manure from antibiotics‐treated animals can thus spread resistance genes to the human gut microbiome and further the emergence of multi‐drug‐resistant human pathogens. The widespread application of pesticides and herbicides could similarly increase the risk of new pathogens and diseases against both plants and humans.
… crop plants today lack many of their important symbiotic partners to produce or increase the contents of vitamins, minerals, antioxidants and other metabolites…
Recent research suggests that the root and gut microbial communities exist under similar conditions (Mendes & Raaijmakers, 2015). Both are open systems characterized by gradients of oxygen, water and pH that create a diversity of different niches. Both systems inherit their microbial members from the environment: food in humans and soil in plants, respectively. Plant and gut systems are populated by a multitude of similar bacterial phyla (Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria) and, similar to human faecal transfer, transplantation of beneficial microbes from disease‐suppressive soils can protect plants against various diseases (Mendes & Raaijmakers, 2015). Research on different mammalian herbivores and carnivores indicates that the gut microbiome recruits some of its members from eating raw plant material. Root and gut microbes synthesize essential amino acids, vitamins and many other secondary metabolites that modulate their host immune system: as such, the plant and gut microbiomes can be considered as meta‐organs with paramount importance for the health of their hosts.
Most of our daily food comes from industrial agriculture and has been exposed to herbicides, fertilizers and a large array of pesticides to obtain high yields.
It is therefore important to better understand the functions and roles of the hundreds of different microbial species in the complex interaction network with their hosts. Of equal importance is the question how to establish and maintain a healthy microbiome. At the same time, the re‐integration of beneficial microbes into agriculture could contribute to providing healthy food in a sustainable manner so as to help reduce the amount of fertilizer, pesticides and herbicides being used (Bender et al, 2016). Moreover, given the food link, humans would also benefit from eating unprocessed organic food since it supplies beneficial microbes along with secondary metabolites. Research on the integral role of microbiomes on their host’s metabolism and health should therefore not stop at the human gut microbiome but expand to the microbiota of plants and their function in plant growth and development. Given the food link, such an effort would benefit both plants and humans.
The work was supported by the baseline fund BAS/1/1062‐01‐01 to HH from the King Abdullah University of Science and Technology.